机构地区: 广东工业大学轻工化工学院
出 处: 《化学研究与应用》 2011年第10期1349-1352,共4页
摘 要: 以抗肿瘤药物分子冬凌草甲素为模板,甲基丙烯酸(MAA)为功能单体,乙二醇二甲基丙烯酸酯(ED-MA)作交联剂,采用沉淀聚合法和本体聚合法,制备对冬凌草甲素具有特定亲和选择性的分子印迹聚合物,并用激光粒度扫描和扫描电镜对聚合物的粒径和表面形貌进行了表征,采用平衡结合实验评价了两类分子印迹聚合物的吸附性能。结果表明,与使用本体聚合法制备得到的无定形颗粒相比,沉淀聚合方法所制备的印迹聚合物表现出较好的特异吸附,对模板分子最大净吸附量值为31.5μmol/g,显示出良好的选择识别能力。 Abstract In this study,the specific imprinted polymers were synthesized by the precipitation polymerization and the bulk polymerization methods by utilizing oridonin as a template molecule,methyl acrylic acid(MAA)as a functional monomer,ethylene glycol dimethyl acrylate(EDMA)as the cross-linkers.The polymers were characterized by laser particle size scanning and scanning electron microscopy.The binding performance of the imprinted polymers was evaluated using equilibrium experiments.The results showed that the imprinted polymer prepared by using the precipitation polymerization method possessed better specific adsorbed capacity and molecular recognition ability in contrast with the conventional bulk polymers,and the specific adsorption value toward template reached 31.5 μmol/g.