作　　者： ; ; ; ;

机构地区： 东莞理工学院化学与环境工程学院

出　　处： 《东莞理工学院学报》 2011年第5期35-38,59,共5页

摘　　要： 利用Novozyme-435酶催化2,2-双(羟甲基)丙酸苄基酯与癸二酸的缩聚反应,再在同一体系中加入己内酯进行酶催化开环反应。反应监测结果表明了,利用酶催化,两种不同的聚合反应在同一反应容器中成功进行并生成了嵌段聚合物。利用动态光散射仪测定了此嵌段聚合物在水溶液中的自组装形成胶束的行为,并利用原子力显微镜观察了固定化后的胶束的形貌。 Enzymatic polycondensation of benzyl-2,2-bis （methylol） propionate and sebacic acid has been performed by using lipase Novozyme-435 as a catalyst, subsequently enzymatic ring-opening polymerization is reacted by adding e-eaprolactone as the monomer in the same system. The reaction monitoring results indicates that two different modes of polymerization, as above mentioned, successively take place through enzyme catalysis in one-pot to produce the block copolymer successfully. The self-assembly of the copolymer into aggregation micelles in aqueous media is determined by dynamic light scattering（DLS） and the morphology of these solventless micelles is observed by atomic force microscopy （ AFM ）.

关 键 词： 酶催化 自组装 双嵌段共聚物

领　　域： [化学工程]