作　　者： ; (刘福胜）;

机构地区： 齐鲁石化公司研究院有机化工研究所山东淄博255400

出　　处： 《精细化工》 1999年第5期51-54,共4页

摘　　要： 采用ｗ（Ｐｄ）＝５％ 的ＰｄＣ为催化剂，Ｖ（水） Ｖ（乙醇） ＝１∶１ 的混合液为溶剂，对６氯９苄基９Ｈ嘌呤、６氯９四氢吡喃２基９Ｈ嘌呤和６氯２氨基９苄基９Ｈ嘌呤等氯代嘌呤衍生物的加氢脱氯反应进行了研究，在反应温度为室温，Ｈ２ 压力为３０３ｋＰａ，催化剂用量为反应物质量的１５％ ，反应时间３ｈ 的较佳工艺条件下，产品收率大于９０％ 。用１ ＨＮＭＲ、１３ The hydrogenating dechlorination of 6 chloro 9 benzyl 9H purine,6 chloro 9 tetrahydropuran 2 yl 9H purine and 6 chloro 2 amino 9 benzyl 9H purine was studied using 5% Pd/C as catalyst and V(H\-2O)/V(EtOH)=1∶1 as solvent.The optimum reaction conditions were as follows:reaction temperature room temperature,H\-2 pressure 303kPa,amount of catalyst 15%,reaction time 3h.The yields of the products were above 90%.The products were characterized by \+1 H NMR,\+\{13\}C NMR and MS.

关 键 词： 加氢 脱氯 氯代嘌呤 嘌呤衍生物

领　　域： [化学工程]