作　　者： ; ; ;

机构地区： 南京体育学院

出　　处： 《南京体育学院学报（自然科学版）》 2010年第1期1-3,共3页

摘　　要： 50只SD雄性成年大鼠分别接受不同时间的水应激、一次性力竭游泳运动和长期游泳耐力训练,用免疫印迹法检测中脑TH含量,以荧光发光分析法检测纹状体DA含量。结果显示:长期游泳训练与安静状态的大鼠和一次性力竭游泳大鼠相比中脑TH含量有升高的趋势,但以上变化并没有显著性差异;而一次性力竭游泳运动使得大鼠纹状体DA含量高与安静组,长期游泳耐力训练引起了大鼠纹状体DA含量显著性升高;处于一次性水环境与长期水环境的大鼠中脑TH与纹状体DA含量无显著性差异;长期耐力游泳训练大鼠中脑TH和纹状体DA含量显著性高于处于水环境的大鼠。提示:一次性力竭游泳运动抑制了中脑TH活性,而长期游泳耐力训练有助于提高大鼠中脑TH含量,增加纹状体DA的释放量,提高中枢兴奋性,从而能够改善中枢机能,延迟中枢疲劳的发生时间;水环境会抑制大鼠中脑TH含量,从而使机体处于中枢抑制状态,建议在建立大鼠游泳训练模型中,应增列水环境对照组,从而增强实验的可比性与真实性。 This study focused on the changes of tyrosinehydroxylase（TH）,dopamine（DA） concentration in corpus striatum,midbrain of rat after water environment stress,acute exhaustion swimming and long time swimming training.Western blotting and fluorescence spectrophotometer was used for evaluating the amounts of TH and DA.TH level in corpus striatum of control and long time swimming group were higher than actute exhaustion swimming group,but there was no significant difference.DA level in midbrain of acute exhaustion swimming and long time swimming training had a rising trend than control group,especially long time swimming group higher significantly.Change of DA and TH level had no difference between water environment stress groups.DA and TH concentration of long time swimming training group was increased significantly than water environment stress groups.These observations suggest that long time swimming training could improve function and suppress fatigue of brain in rats.Water environment maybe decrease the function of brain in rats,so adding a water environment control group,which can reduce the statistical difference,is necessity.

关 键 词： 运动负荷 水应激 中枢疲劳

领　　域： [文化科学] [文化科学]