作　　者： ; ; ; ;

机构地区： 广东食品药品职业学院化妆品科学系

出　　处： 《日用化学工业》 2010年第2期94-97,共4页

摘　　要： 采用饱和水溶液法制备阿魏酸(FA)的α-环糊精(α-CD)包合物。通过差示扫描量热法(DSC)、X射线衍射法(XRD)和核磁共振法(1HNMR)对包合物进行验证,并对FA在包合前后的光稳定性进行了测试。结果表明,α-CD内侧质子及H-4发生较明显化学位移;FA的H-e和H-f发生了较明显的向低场位移。提示FA作为客体分子部分进入α-CD空穴,FA/α-CD包合体已经形成,包合物摩尔比为1∶1。包合前后的抗光解性差异显著(P<0.05)。 Inclusion compound composed of ferulic acid （FA）/α -cyclodextrin （α-CD） was prepared with saturated aqueous solution method, and characterized by differential scanning calorimetry （DSC）, X- ray diffractometry （XRD）,and 1^H nuclear magnetic resonance （1^H NMR） spectroscopy. The photostability of free FA and FA/α - CD was tested and compared. Result showed that a significant change was observed in the chemical shift of proton H - 4 and other protons inside cavity in the CD. And a significant downfield change was also observed in the chemical shift of the proton H - e and H - f of FA. Which indicates that FA is partly included inside the molecular tube and FA is capable of forming 1 ： 1 inclusion compound with α - cyclodextrin. The photostability of FA/α - CD is significantly different from free FA （ P 〈 0.05 ）.

关 键 词： 化妆品添加剂 阿魏酸 环糊精包合物 制备 结构表征

领　　域： [化学工程]