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人工感染小鹅瘟的病理形态学研究
PATHOMORPHOLOGICAL STUDY ON EXPERIMENTAL GOSLING PLAGUE

作  者: ;

机构地区: 四川农业大学动物科技学院

出  处: 《畜牧兽医学报》 1998年第4期377-384,共8页

摘  要: 40只雏鹅口服感染小鹅瘟病毒,在不同感染阶段剖杀雏鹅,观察各组织器官的病理变化发展规律及病理特征。接种后第1天,小肠绒毛顶部上皮首先发生坏死脱落。随着感染时间的延长,坏死、脱落向绒毛基部发展,同时,固有膜也相继发生坏死和炎性细胞浸润。由于小肠的坏死和炎性渗出逐步加剧,最后发展成为纤维素性坏死性肠炎,并在小肠的中下段形成特征性的凝固性栓子,堵满肠腔。实质器官普遍发生变性和炎性细胞浸润。肝、胰、脾、胸腺、腔上囊,发生灶性坏死。电镜观察,病毒首先损害小肠绒毛顶部上皮,心肌和肝细胞线粒体肿胀,嵴断裂,消失,基质变空,内质网扩张,核染色质溶解。 お?0 fivedayold goslings were experimentally infected with gosling plague virus by oral administrationThe infected goslings were killed at distinct postinfection stagesThe first changes were found in the small intestineThe epithelial cells at the villus tip fell off on the first day postinfectionThen necrosis and slough went down to the bases of the villusMeanwhile,the necrosis and infiltration with the inflammatory cells occurred in the membrana propriaAlong with the aggravatin of these changes,the fibrinous necrotic enteritis appeared in the small intestine ,especially,in the middlelower sections of the small intestineAs a result,a particular coagulative embolus occurred and blocked up the intestinal cavityParenchymatous organs showed degeneration and infiltration with the inflammatory cellsFacal necrosis was seen in the liver,spleen,pancreas,thymus,bursa of FabriciusObservation throught electron microscope proved that the virus first affected the epithelial cells at the villus tip of the small intestinesThe mitochondria in the cells of the heart and liver swelledThe crest became short or disappeared,and ground substance emptiedAlso,endoplasmic reticulum dilated

关 键 词: 小鹅瘟 病理形态学 超微结构

领  域: [农业科学] [农业科学] [农业科学] [农业科学] [农业科学] [农业科学]

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机构 华南师范大学生命科学学院生物科学系
机构 中山大学生命科学学院生物系
机构 华南师范大学

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