作　　者： ; ; ; ; ; ;

机构地区： 西北工业大学材料学院

出　　处： 《高分子材料科学与工程》 2009年第6期158-162,共5页

摘　　要： 传统智能水凝胶作为药物载体可控制药物的定点、定时、定量释放,具有提高药效、靶向,减少给药频率,增加安全性等优点。但由于存在响应速率慢的缺点而大大限制其应用。因此,近年来围绕提高智能水凝胶给药的响应速率的研究非常活跃,展示了广阔的应用前景。文中综述了快速响应水凝胶的类型、制备原理与给药系统中的应用进展,并指出其缺点及发展方向。 The traditional intelligent hydrogels as drug carriers can control the drugs to release in location, time, and quantity, and have the advantages of improving efficacy, targeting, reducing dose frequency, increasing security, etc. But their applications are greatly limited for the existence of the shortcoming of the slow response rate. So, focusing on improving the intelligent hydrogels response rate has been extensively studied in recent years, and has showed broad application prospects. In this paper, the latest progress in drug delivery system, category and preparation principle of rapid responsive hydrogels were reviewed, and their disadvantages and developing direction were pointed out.

关 键 词： 快速响应 水凝胶 给药系统

领　　域： [化学工程]