作　　者： ; ; ; ; ; ;

机构地区： 深圳大学化学与化工学院

出　　处： 《现代化工》 2007年第S2期290-292,296,共4页

摘　　要： 以二乙基二硫代氨基甲酸钠(NaDDC)作为配合剂,乙醇为改性剂,采用超临界CO2配合萃取广东道地药材巴戟天中有害元素Cu、Pb、As。考察了配合萃取方式、萃取时间、萃取压力、温度、配合剂用量等因素对中药材中有害元素的影响。通过正交实验,建立了有害元素脱除工艺为:萃取压力28 MPa,萃取温度60℃,m(药材)∶m(NaDDC)=5∶1,m(药材)∶m(乙醇)=1∶1,静态萃取1 h,动态萃取2 h。在此条件下,巴戟天中Cu、Pb、As的脱除率均达60%以上,萃取后的药材中有害元素量含量达到美国FDA标准,研究成果为中药材中有害元素的脱除开辟了一条新途径。 Harmful elements of copper,lead and arsenic are removed from Morinda officinalis How,a Chinese traditional medicine,by supercritical carbon dioxide with sodium diethyldithiocarbamate(NaDDC) as a chelating agent and ethanol as a modifier.The effects of extraction style,pressure,temperature,time and amount of chelating agent on chelating extraction process are discussed.The optimum condition was established by orthogonal designs as following:25 MP as extraction pressure,60℃ as extraction temperature,1 h as static extraction time,2 h as dynamic extraction time,m(herb)∶m(NaDDC)=5∶1,m(herb)∶m(ethanol)=1∶1.Under thess conditions,the extraction rate of Cu,Pb and As was up to 60%,which reached US FDA standard.The results showed chelating extraction by supercritical CO2 provided a new way to decrease the content s of harmful elements from Chinese traditional medicines.

关 键 词： 超临界 有害元素 配合 中药材 巴戟天

领　　域： [化学工程]