作　　者： ; ; ; ; ; ; ;

机构地区： 三峡大学化学与生命科学学院

出　　处： 《中山大学学报（自然科学版）》 2007年第6期59-62,共4页

摘　　要： Bacillosporin C,D及3个Xanthones类化合物:1,3,6-三羟基-8-甲基-Xanthone,Griseoxanthone C,Sterig-matocystin是中国南海红树林内生真菌SBE-14的次级代谢产物,Bacillosporin C和D是一类含7个环结构特殊的化合物,是首次从海洋真菌分离得到,其药理活性未见报道。药理活性试验结果表明Bacillosporin C和D有强的抑制KB细胞活性,Griseoxanthone C有强的抑制Hep2细胞的活性,Sterigmatocystin只有弱的抑制Hep2细胞的活性。 Bacillosporin C , D , 1, 3, 6-trihydroxyl-8-methyl-xanthone, griseoxan thone C, and sterig-matocystin were the metabolites of mangrove endophytic fungus SBE-14 from South China Sea. The chemical structures of Bacillosporin C and D are special, whith contain seven cycles. Bacillosporin C and D were firstly isolated from marine fungus, and their bioactivities were not reported. In our primary inhibiting KB and Hep2 cells experiments, the results showed that bacillosporin C and D indicated strong inhibiting KB cells activities and griseoxanthone C showed strong inhibiting Hep2 cells, but sterigmatocystin showed almost no activity to Hep2 cells.

关 键 词： 红树林内生真菌 次级代谢产物 生理活性

领　　域： [理学] [理学]