机构地区: 西安文理学院
出 处: 《成都体育学院学报》 2007年第6期98-101,共4页
摘 要: 分别采用R IA法、硝酸还原酶法、化学比色法,检测大鼠海马中ET、CGRP、NO含量及NOS活性。结果:力竭组大鼠海马中ET、NO含量及NOS活性显著高于对照组,CGRP含量明显低于对照组(P<0.05);而训练组海马中ET、CGRP、NO含量及NOS活性与对照组无显著性差异(P>0.05)。结论:力竭运动即刻海马中ET、NO含量及NOS活性显著升高,CGRP显著下降,可能是中枢性疲劳的机制之一;而训练运动可降低急性力竭运动大鼠海马中ET、NO含量及NOS活性,提高CGRP含量,发挥中枢保护作用。 This study is to explore the effects of exhausting exercise and train exhausting exercise on the contents of ET, CGRP, No and the activity of NOS in the hippocampus of rats. Methods : the contents of ET, CGRP, No and the activity of NOS in the hippocampus of rats are determined by radioimmunoassay,nitrate reductase and chemical chromatometry. Results: exhausting exercise can increase the contents of ET,NO and the activity of NOS but decrease the contents of CGRP in the hippocampus of rats in contrast with the control group ( P 〈 0.05 ). And there is not significance difference between the group of train exhausting exercise and control group on the contents of ET, CGRP, No and the activity of NOS ( P 〉 0.05). Conclusion : the instantly increased contents of ET, NO and the activity of NOS and decreased contents of CGRP in the hippocampus of rats may be one of the mechanism of central fatigue. However, train exhausting exercise can protect the central system by decreasing the contents and activity of ET,NO and NOS and increasing the contents of CGRP in the hinnocamnus of rats.