作　　者： ;

机构地区： 四川农业大学动物科技学院

出　　处： 《四川农业大学学报》 1997年第2期255-262,共8页

摘　　要： 口服感染４０只雏鹅小鹅瘟病毒，在不同感染阶段剖杀雏鹅，观察各组织器官的病理变化发展规律及病理特征。接种后第１天，小肠绒毛顶部上皮首先发生坏死脱落。随着感染时间的延长，坏死、脱落向绒毛基部发展，同时，固有膜也相继发生坏死和炎性细胞浸润。由于小肠的坏死和炎性渗出逐步加剧，最后发展成为纤维素性坏死性肠炎，并在小肠的中下段形成特征性的凝固性栓子，堵满肠腔。实质器官普遍发生变性和炎性细胞浸润。肝、胰、脾、胸腺、腔上囊，发生灶性坏死。电镜观察，病毒首先损害小肠绒毛顶部上皮，心肌和肝细胞线粒体肿胀，嵴断裂，消失，基质变空，内质网扩张。 five-day-old goslings were experimentaly infected with gosling plague virus by oral administration. The infected goslings were killed at distinct postinfection stages. The first changes were found in the small intes-tine.The epithelial cells at the villus tip fell off in the first day postinf-ection.Then necrosis and falling went down to the bases of the villus.Meanwhile,the necrosis and infiltration with the inflammatory cells occurred in the membrana propria. Along with those changes aggravating, the fibrinous necrotic enteritis showed in the small intestine, especially,the middle-lower sections of the small intestine. As a result, a particular coagulative embolus took shape,and blocked up the intestinal cavity.Parenchymatous organs appeared degeneration and infiltration with the inflammatory cells. Liver, spleen, pancreas, thymus,bursa of Fabricius necrosed focally. Observing through electron microscope, the virus first damaged the epithelia cells at the villus tip of the small intes-tines. The mitochondria in the cells of the hear and liver swelled. The crestbecam short or disappeared,and ground substance empty.Also,endoplasmic reticulum dilated.

关 键 词： 小鹅瘟 病理形态学 超微结构 病理学 鹅病

领　　域： [农业科学] [农业科学] [农业科学] [农业科学] [农业科学] [农业科学]