作　　者： ; ; ;

机构地区： 华南理工大学轻工与食品学院

出　　处： 《化工学报》 2007年第6期1541-1547,共7页

摘　　要： Chlorogenic acid (CGA) is a natural antioxidant, and nowadays it has been used in medicine, food processing and cosmetic industry.However, to a certain extent its application is restricted because it is only soluble in water but is lipo-insoluble.In this research, liposoluble chlorogenic laurate(CGL) was synthesized by acylation with lauroyl chloride (LC) in the presence of triethylamine (TEA) in non-water phase.It was found that the optimized synthesis conditions were as follows: with dimethylformamide (DMF) as the dissolution agent and thinner, n CGA∶n LC∶n TEA=1∶1∶1.5, temperature(35±1)℃ and reaction time 8 h.Under these conditions a light yellowish powder was obtained and the yield of CGL was 81.24 %.The structure of CGL was characterized by UV-Vis, IR, ESI-MS and 1H NMR. Theoretically, the method of quantum chemistry calculation was used to demonstrate the feasibility and rationality of molecular modification for CGA.Meanwhile, the result of the test of the use of CGL on Guangdong-type sausage showed that 0.05% of CGL could increase the antioxidant ability of the products. Chlorogenic acid （CGA） is a natural antioxidant, and nowadays it has been used in medicine, food processing and cosmetic industry. However, to a certain extent its application is restricted because it is only soluble in water but is lipo-insoluble. In this research, liposoluble chlorogenic laurate （CGL） was synthesized by acylation with lauroyl chloride （LC） in the presence of triethylamine （TEA） in non-water phase. It was found that the optimized synthesis conditions were as follows, with dimethylformamide （DMF） as the dissolution agent and thinner, n CCA ： nLC： nTEA=1： 1： 1. 5, temperature （35±1）℃ and reaction time 8 h. Under these conditions a light yellowish powder was obtained and the yield of CGL was 81.24 %. The structure of CGL was characterized by UV-Vis, IR, ESI-MS and ^1H NMR. Theoretically, the method of quantum chemistry calculation was used to demonstrate the feasibility and rationality of molecular modification for CGA. Meanwhile, the result of the test of the use of CGL on Guangdong-type sausage showed that 0.05 % of CGL could increase the antioxidant ability of the products.

关 键 词： 分子修饰 绿原酸月桂酸酯 脂溶性 量子化学计算

领　　域： [理学] [理学] [轻工技术与工程] [轻工技术与工程]