作　　者： ; ; ; ; ;

机构地区： 广东省农业科学院

出　　处： 《动物营养学报》 2007年第2期135-141,共7页

摘　　要： 本文旨在研究谷氨酰胺二肽(Gln二肽)对断奶仔猪生长、免疫、抗氧化力和小肠粘膜形态的影响,探讨Gln二肽缓减仔猪断奶应激的机理。选用96头平均体重(6.23±0.13)kg杜×(大×长)三元杂交仔猪,按完全区组设计分为4组,每组4个重复,每个重复6头(公母各1/2),各处理仔猪分别饲喂基础饲粮、基础饲粮添加0.125%Gln二肽、基础饲粮添加0.25%Gln二肽和2%血浆蛋白粉的试验饲粮。结果表明,饲粮中添加0.125%和0.25%Gln二肽可以提高断奶仔猪生长性能。其中,断奶后0～10d0.125%Gln二肽组的生长性能与2%血浆蛋白粉组相近;断奶后11～21d0.125%Gln二肽组的生长性能略优于2%血浆蛋白粉组(P>0.05),而每kg增重饲料成本显著低于2%血浆蛋白粉(P<0.05)。随饲粮Gln二肽添加水平提高,断奶后第10天血液中CD4+数量以二次曲线方式升高(二次,P=0.08),第10和第21天血清GSH-Px活性分别以线性(线性,P=0.02)或二次曲线(二次,P=0.10)方式升高,第10和第21天血清SOD活性均以线性方式升高(线性,P=0.10和0.08)。断奶后第21天,0.125%Gln二肽组十二指肠的隐窝深度显著低于基础饲粮组(P<0.05)。总之,Gln二肽可能通过增强断奶仔猪细胞免疫功能、改善抗氧化能力、防止小肠粘膜绒毛萎缩,以缓减仔猪的断奶应激,从而提高生长性能,且以0.125%Gln二肽组仔猪生长性能最好,每kg增重饲料成本最低。 This trial was conducted to study the effect of glutamine （Gin） dipeptide on growth, immunity, antioxidance and small intestinal mucosa morphology of weanling piglets to investigate mechanism of alleviating weanling stress. Ninety six crossbred Duroc × （Landrace × Largewhite） weanling piglets of weighing （6.23±0.13） kg were allocated to 4 treatments with 4 replicates of 6 piglets each （half male, half female）. Piglets per treatment were respectively fed one of the experimental diets supplemented with 0%, 0. 125% and 0.25% Gin dipeptide and 2% spray dried plasma protein （SDPP）. The results indicated that the supplementation of 0. 125% and 0.25% Gin dipeptide improved growth performance, and the effect of 0. 125% Gin dipeptide in improving growth performance reached or exceeded those of 2% SDPP （P〉0.05）, however, feed cost per kg gain of 0. 125% Gin dipeptide was lower than that of 2%SDPP （P〈0.05）. With the increasing Gin dipeptide supplementation levels, CD4^＋ in blood was increased （quadratic, P=0.08） on 10 day, serum GSH-Px activity was respectively increased （linear, P=0.02 and quadratic, P=0.10 ） on 10 and 21 day, serum SOD activity was increased （linear, P = 0.10 and 0.08 ） on 10 and 21 day. Crypt depth of 0. 125%Gin dipeptide was significant lower than that of control on 21 day post-weanling. Gin dipeptide might alleviate stress of weanling piglets through strengthening cell immunity, improving antioxidance and protecting from atrophy of small intestinal mucosa villus. Supplementation of 0. 125% Gin dipeptide not only had the best effect, but also had the lowest feed cost per kg gain.

关 键 词： 谷氨酰胺二肽 断奶仔猪 生长 免疫 抗氧化力 小肠粘膜形态

领　　域： [农业科学] [农业科学] [农业科学]