机构地区: 广西师范大学化学化工学院
出 处: 《有机化学》 2006年第12期1623-1630,共8页
摘 要: 综述了近年来2-碘酰基苯甲酸(2-iodoxybenzoicacid,IBX)在有机合成中的应用,重点评述了IBX对醇类、含氮有机物、含硫有机物、连接在芳环上的碳原子的氧化反应,探讨了IBX在α,β-不饱和羰基化合物和内酯合成中的应用,这些反应具有反应条件温和、产率高、选择性好等优点.简单介绍了IBX的一些新衍生物的合成及应用. This paper reviews the applications of 2-iodoxybenzoic acid (IBX) in organic synthesis, focusing on the oxidations of IBX with alcohols, nitrogen-containing, sulfur-containing organic compounds, selective oxidation at carbon adjacent to aromatic systems, preparations of α,β-unsaturated carbonyl compounds and lactones, etc. These reactions take place in mild conditions, in high yields, and with high chemoselecticity. IBX-amide, IBX-ester and polymer-supported IBX analogues, which are mild, non-explosive, highly soluble, and/or recyclable, are also discussed.