作　　者： ; ; ;

机构地区： 湖南长沙卷烟厂长沙410000

出　　处： 《理化检验（化学分册）》 2006年第8期604-607,共4页

摘　　要： 采用自组装方法制备了卡托普利（CPT）修饰电化学传感器，并对其在金电极表面形成的单分子膜进行了表征。循环伏安试验结果表明，辅酶Q在CPT修饰电极上能发生准可逆的电化学反应。该传感器对辅酶Q测定具有良好的响应，测定范围为5．0×10^-6～6．0×10^-5mol·L^-1，检出限为2．0×10^-6mol·L^-1，异相电子传递速率常数k3为5．4×10^-3cm·s^-1。对CPT修饰膜的稳定性进行考察，讨论辅酶Q发生电化学反应的异相电子传递速率常数k5及其影响机制。 An electrochemical sensor of captopril （CPT） modified, selfassembled Art-electrode was prepared, and the formation of mono-molecular membrane on the surface of Au-electrode was characterized. As shown by the results of the study of electrochemical behavior of coenzyme Q （CZM Q） at the CPT modified electrode, the electrode reaction was an one electrontransferring quasi-reversible reaction, and linear response in the concentration range of 5.0×10^-6～6.0×10^-5mol·L^-1 of CZM Q was obtaioned, with a detection limit of 2.0×10^-6mol·L^-1. The constant of rate of heterogeneous electron-transfer （k5） was determined and its value calculated by the Nicholson method was 5. 5.4×10^-3cm·s^-1 , and the mechanism of factors affecting the value of ks of electrode reaction of CZM Q at the electrode was discussed. Conditions affecting the stability of the CPT modified electrode was also examined.

关 键 词： 自组装 修饰电极 卡托普利 辅酶 电化学传感器

领　　域： [理学] [理学]