作　　者： ; ; ; ; ;

机构地区： 安徽师范大学化学与材料科学学院功能性分子固体省部共建教育部重点实验室

出　　处： 《分析试验室》 2006年第6期9-11,共3页

摘　　要： 研究发现在碱性条件下,头孢克洛对Luminol-H2O2体系的化学发光有较强的增敏作用,据此建立了流动注射化学发光测定头孢克洛药物的新方法.头孢克洛在1.0×10^-8～2.0×10^-5g/mL范围内与发光信号的增强值（△I）呈良好的线性关系;检出限（3δ）为6.0×10^-9g/mL;对于1.0×10^-6g/mL头孢克洛进行11次测定,相对标准偏差为2.2%.应用于希刻劳颗粒中头孢克洛的测定. A novel flow injection method was developed for the determination of cefaclor based on the enhancement of cefaclor on the chemiluminescence of Luminol-H2O2 system. The method is simple, selective and sensitive with a detection limit of 6.0 × 10^-9 g/mL. It is effective to determine cefaclor in the range of 1.0 × 10^-8～2.0 ×10^-5 g/mL. The relative standard deviation is 2.2% for the determination of 1.0 ×10^-6 g/mL cefaclor （ n = 11 ）. The proposed method has been successfully applied to determination of cefaclor in Xikelao granules with satisfactory results.

关 键 词： 化学发光 鲁米诺 头孢克洛

领　　域： [理学] [理学]