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喹赛多对仔猪产肠毒素大肠杆菌感染的预防效果
Prophylactic Effect of Cyadox on Experimental Enterotoxigenic Escherichia coli Infection in Piglets

作  者: ; ; ; ; ;

机构地区: 华中农业大学

出  处: 《中国兽医学报》 2005年第6期643-645,648,共4页

摘  要: 150只去势长大仔猪随机分为6组,Ⅰ和Ⅳ组饲喂不含抗菌药的基础日粮,Ⅱ和Ⅴ组基础日粮中添加喹乙醇100m g/kg,Ⅲ和Ⅵ组基础日粮中添加喹赛多100 m g/kg。Ⅳ、Ⅴ和Ⅵ组仔猪灌服1010CFU产肠毒素性大肠杆菌(O139∶K88),Ⅰ、Ⅱ和Ⅲ组仅灌服肉汤。结果表明,喹赛多饲喂猪直肠粪便中大肠杆菌总数和接种的血清型大肠杆菌数与喹乙醇饲喂猪均无显著差异(P>0.05),喹赛多和喹乙醇饲喂猪直肠粪便中接种的血清型大肠杆菌数均低于非药物饲喂猪(P<0.05)。Ⅳ组仔猪感染率为68%;Ⅴ和Ⅵ组感染率均为16%。药物饲喂猪平均日增重显著改善(P<0.05),喹赛多饲喂猪平均日增重高于喹乙醇饲喂猪(P<0.05)。Ⅳ组仔猪平均日增重和饲料转化率分别下降9.6%和8.4%,Ⅵ组仔猪日增重和饲料转化率分别提高11.9%和7.9%,均高于Ⅴ组(4.2%和1.5%)。可见喹赛多不仅对断奶仔猪产肠毒素大肠杆菌感染有显著预防作用,而且还有较好的促进生长和提高饲料转化率作用。 One hundred and fifty Landrace × Large-White geld piglets were randomly allotted to six groups of 25 each. Pigs in group 1 and group 4 were given basal diet without any medicine,pigs in group 3 and 6 being fed basal diet supplemented with 100 mg/kg cyadox,and pigs in group 2 and 5 being fed basal diet supplemented with 100 mg/kg olaquindox. Pigs in group 4,5 and 6 were orally given 10^10 CFU of Escherichia coli(E, coli,0139 : K88) while pigs in group 1,2 and 3 were given equal volume of alkaline broth as a placebo. There were no differences(P〉0. 05) in the fecal shedding of total E. coli or the inoculated E. coli between olaquindox-supplemented pigs and cyadox-supplemented pigs. However,the fecal shedding of the inoculated E. coli in the olaquindox-or cyadox-supplemented was lower(P〈0. 05) than that in the inoculated control. The incidences of Escherichia coli infection in group 6 and 5 were both 16 %,lower (P〈0.01) than that in group 4 (68 % ). Average daily gain (ADG) was improved by the additives (P〈0. 05). ADG in the cyadox-supplemented was higher than that in the olaquindox-supplemented. ADG and feed conversion ratio(FCR) in group 6 were improved by 11.9% and 7.9% respectively,higher than those in group 5 (4.2% and 1.5% ) ,whereas ADG and FCR in group 4 were decreased by 9.6% and 8.4%. These results indicated that cyadox can not only prevent Escherichia coli infection efficiently,but also improve ADG and FCR significantly.

关 键 词: 喹赛多 产毒素性大肠杆菌 预防 生长性能

领  域: [农业科学] [农业科学] [农业科学] [农业科学] [农业科学] [农业科学]

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