作　　者： ; ; ; ; ;

机构地区： 广州出入境检验检疫局

出　　处： 《食品科学》 2005年第9期482-483,共2页

摘　　要： 目的:采用动物实验对进口保健食品元秘-D的抗疲劳作用进行了鉴定。方法:急性毒性半数致死量(LD50)实验,30d喂养实验,转轮实验,游泳实验。结果:元秘-D对小鼠无明显的急性毒性作用,LD50>10g/kg体重。在30d小鼠喂养实验中,实验组和对照组的小鼠生长发育正常,体重和脏器系数无明显差异,一次给予元秘-D后,实验组的转轮时间和游泳时间都明显较对照组延长(p<0.05和p<0.01)。30d喂养实验后,实验组的转轮时间和游泳时间较对照组均有延长的趋势(p>0.05)。结论:元秘-D对小鼠有一定的抗疲劳作用,可安全服用。 Objective： The anti-fatigue effect of Yuanmi-D,a kind of import health food,was identified with a series of animal tests.Methods：The acute toxicitity LD50 test in mice,30 days feeding test ,wheel rotation test, swim test. Result： Yuanmi-D had no apparent acute toxicity on mouse, LD50〉10g/kgBW.During the 30 days of mouse feeding,all the mice in the treated group and the control group grew normally.The mouse bodyweight and the organ index had no apparent difference between the two groups.Wheel rotation time and swim time in the treated group lasted longer apparently than in the control group（p〈0.05 and p〈0.01） after first Yuanmi-Dfeeding.There was a trend of longer wheel rotation time and swim time in the treated group than in the control group after 20 days feeding（p 〉 0.05）.Conclusion： Yuanmi-D was safe in use, and there were some anti-fatigue function in Yuanmi-D on mice.

关 键 词： 元秘 抗疲劳 转轮实验 游泳实验

领　　域： [轻工技术与工程] [轻工技术与工程]