作　　者： ; ; ; ; (陈杖榴）;

机构地区： 华南农业大学动物科学学院

出　　处： 《农业环境科学学报》 2005年第4期698-700,共3页

摘　　要： 恩诺沙星是在畜禽养殖业中得到广泛应用的抗菌药物。以隆腺蚤(DaphniaCarinata)为试验对象,测定了恩诺沙星对隆腺蚤的急性毒性。结果表明,25℃时,24h恩诺沙星对隆腺蚤的最大不致死浓度为1μg·mL-1,使隆腺蚤全部死亡的最低浓度为120μg·mL-1;恩诺沙星在24h、48h时对隆腺蚤的EC50分别为34.03μg·mL-1和19.37μg·mL-1。48h时,恩诺沙星对隆腺蚤的LC50为25.86μg·mL-1。依据蚤类急性活动抑制毒性分级标准,恩诺沙星对于隆腺蚤属于中毒性化合物。 Enrofloxacin is a kind of antibiotics extensively applied in animal husbandry. After application, it would not only remain in the product of animals, but also enter the environment through the excrement. The acute immobilization toxicity of enrofloxacin to Daphnia Carinata at 25℃ was studied, in which eight treatments of different concentrations of enrofloxacin and one blank group were included. At 24 h, the minimum concentration was 1μg·mL^-1 that could not make Daphnia Carinata die and the minimum concentration was 120μg·mL^-1 that made Daphnia Carinata die all. The sensitivity of Daphnia Carinata to enrofloxacin increased with the time extension or the concentration increasing. The EC50 （effective concentration for 50% reduction） and LC50 （lethal concentration for 50%） of enrofloxacin was calculated using the method of probability unit. The 24h-EC50 and 48h-EC50 of enroflocxacin to Daphnia Carinata were 34.03μg·mL^-1 and 19.37 μg·mL^-1 respectively, and the 48h-LC50 was 25.86μg·mL^-1. According to the standard of acute immobilization toxicity to Daphnia, enrofloxacin was medium-toxin to Daphnia Carinata. When enrofloxacin entered into aquatic ecosystem, its concentration decreased as a result of dilution and the degradation would be very fast, so it had no acute toxicity to Daphnia Carinata in natural water.

关 键 词： 恩诺沙星 隆腺蚤 急性活动抑制毒性

领　　域： [农业科学] [农业科学] [农业科学]