作　　者： ; ; ; ; ;

机构地区： 中国水产科学研究院珠江水产研究所

出　　处： 《动物医学进展》 2005年第7期82-85,共4页

摘　　要： 通过对实验动物化的剑尾鱼进行急性硫酸铜中毒实验,在观察症状和剖检变化以后,对实验96h期间死亡鱼与96h后仍存活的鱼进行石蜡切片,HE染色,光学显微镜观察。主要眼观病变为肝脏水肿和白色坏死点;鳃丝肿胀,黏液分泌增多;肾脏肿胀,充血。显微病变为肝细胞水泡变性,严重坏死;鳃小片上皮细胞肿胀,脱落严重;有的鳃小片发生融合,整个鳃丝呈棒状化;肾小管上皮细胞空泡变性,间质有充血或网织细胞增多,细胞间噬铁血红素细胞增多;肝胰腺的胰腺细胞的酶原颗粒减少。 Toxicity tests were carried out the histopathological changes of the tissues from the fish were abserved to study the toxic effects of copper sulfate on swordtail fish.Swordtail fish(Xiphophorus Helleri) were treated with copper sulfate for 96 h.The results showed that pathological changes observed by eyes were edema and necrosis in livers, swelling and mucus increase in gills, swelling and hyperaemia in kidney. Pathological changes observed by microscope were that damage of the livers included hepatocellular vacuolar degeneration, extensive necrosis; damage to gills included epithelial cell swelled, mucus increased, lamellar epithelium swelled, peeled and claviformed; damage to the kidneys parenchyma included renal tubule epithelial cell granular degeneration, vacuolar degeneration, and damage to interrenal tissues congested and reticulocyte increased; zymogen granule in hepatopancreas decreased.

关 键 词： 剑尾鱼 硫酸铜 急性中毒 病理组织学

领　　域： [农业科学] [农业科学] [农业科学] [农业科学] [农业科学]