作　　者： ; ; ; ; ; ; ;

机构地区： 福州大学化学化工学院福建省功能材料工程研究中心

出　　处： 《无机化学学报》 2005年第7期1069-1072,共4页

摘　　要： A Schiff base ligand 4-[indol-3-yl]-but-3-en-2-one benzoyl hydrazone (HL), and its four transition metal complexes (ML2,M=Cu(, Ni(, Zn( and Co() have been prepared and characterized by means of elemental analysis, EI-MS, molar conductivity, IR, UV-Vis and 1H NMR. The results showed that HL as a bidentate ligand coordinated with transition metal ions to form four-coordination complexes. The antibacterial activity was studied by using the filter scraps diffusion method, and the results indicated that the ligand and the complexes had a low bacteriostatic activity against S. Aureu, P. Aeruginosa and E. Coli. The low in vitro antitumor activity of the title complexes was also observed by using MTT method against KB, A2780, Bel7402 and HELF. A Schiff base ligand 4-[indol-3-yl]-but-3-en-2-one benzoyl hydrazone (HL), and its four transition metal complexes (ML2,M=Cu(II), N(II), Zn(II) and C(II)) have been prepared and characterized by means of elemental analysis, EI-MS, molar conductivity, IR, UV-Vis and H-1 NMR. The results showed that HL as a bidentate ligand coordinated with transition metal ions to form four-coordination complexes. The antibacterial activity was studied by using the filter scraps diffusion method, and the results indicated that the ligand and the complexes had a low bacteriostatic activity against S. Aureu, P. Aeruglnosa and E. Coli. The low in vitro antitumor activity of the title complexes was also observed by using MTT method against KB, A2780, Be17402 and HELF.

关 键 词： 过渡金属配合物 碱 苯甲酰腙 活性研究 合成 丁烯 吲哚 生物 表征 酮

领　　域： [理学] [理学] [理学] [理学]