作　　者： ; ; ;

机构地区： 中山大学生命科学学院生物系

出　　处： 《水生生物学集刊》 1985年第1期74-79,i003-i004,共8页

摘　　要： 在注射低剂量LRH-A的同时注射多巴胺拮抗物pimozide(PIM),能显著增强LRH-A诱导的排卵效应,排卵率达到100％。 LRH-A+PIM能促进脑垂体GtH细胞的合成和分泌,而注射多巴胺能抑制LRH-A诱导的GtH释放活动。 A single injection of low dose LRH-A alone was relatively ineffective for inducing ovulation in Paramisgurnus dabryanus, however, the injection of low dose LRH-A in association with pimozide (PIM), a dopamine antagonist, significantly potentiated the effects of LRH-A on ovulation, the rate of ovulation being 100%. The histological and ultrastructural studies of pituitary showed that the injection of low dose LRH-A together with PIM greatly potentiated the LRH-A stimulated synthesis and release of GtH, whereas the injection of dopamine (DA) blocked the stimulation of GtH release induced by injection of LRH-A. These results demonstrated that dopamine, having GtH release iuhibitory activity in Paramisgurnus dabryanus, acts directly at the pituitary level, so, the combination of treatment with PIM and LRH-A is a highly effective means of inducing ovulation in this fish.

关 键 词： 多巴胺拮抗物 促黄体素释放激素类似物 大鳞副泥鳅 排卵效应 脑垂体 人工繁殖

领　　域： [生物学] [农业科学] [农业科学]