作　　者： ; ; ; ;

机构地区： 重庆大学光电工程学院光电技术及系统教育部重点实验室

出　　处： 《光子学报》 2005年第2期315-318,共4页

摘　　要： 介绍了血液体外循环治疗仪工作原理.对含不同浓度血浆的血液体外循环治疗仪废弃液进行了紫外吸收光谱的实验研究,发现此混合液在278 nm左右存在明显的吸收峰.在血浆紫外吸收光谱的实验基础上,开发出了与血液体外循环治疗仪配套的血浆泄漏监测系统.血浆浓度在0～0.06ml/ml连续变化的废弃液的监测实验结果表明此系统具有较高的灵敏度.在血浆浓度为0 ml/ml、0.015 ml/ml、0.03ml/ml时的连续监测实验结果显示此系统具有良好的稳定性.结论表明基于紫外吸收光谱的血浆泄漏监测系统用于血液体外循环治疗仪治疗过程中的血浆泄漏监测是完全可靠的. Blood circle treatment is a new remedy developed for reducing low density lipoprotein and endotoxin of patients' plasma, consequently, curing or alleviating cardiovascular and cerebrovascular diseases, hypertension and inflammation. However, for there is possibility of plasma leakage before the treated blood is transmitted back to patient and some monitoring procedure is to be maintained. The approach to monitor plasma leakage was presented after a brief introducing of the working principle of the blood circle treatment apparatus. Experiments on ultraviolet absorption spectrum of waste solution of the blood circle treatment apparatus mixed with plasma of different concentration were carried out and, the conclusion that such a solution has an absorption peak at about 278 nm was made. A set of detecting system of plasma leakage suited for the blood circle treatment apparatus was developed with the base of ultraviolet absorption spectrum experiments. In the set double beam scheme was utilized for the optical design of the plasma leakage detecting system to reduce the influence of light source fluctuation. A series of detecting experiments of waste solution interfused 0~0.06 ml/ml plasma show the detecting system possesses relatively high sensitivity. Moreover, the experiments of continual detection with plasma concentration at 0 ml/ml, 0.015 ml/ml and 0.03 ml/ml denote the detecting system provides quite good stability. The detecting system is adapted to dynamically detecting the plasma leakage happened when the blood circle treatment equipment is working.

关 键 词： 紫外吸收光谱 光电检测 血液循环治疗 血浆泄漏 动态监测

领　　域： [电子电信]