作　　者： ; ; ;

机构地区： 华南理工大学食品与生物工程学院

出　　处： 《卫生研究》 2004年第4期508-510,共3页

摘　　要： 随着转基因技术在高等生物中的广泛应用 ,转基因沉默受到越来越多的重视。转基因沉默可发生在转录和转录后两种水平。转基因的甲基化、重复拷贝以及与内源基因的同源序列都可以引起转基因的沉默现象。引起转基因的沉默机制有多种 。 With the widely application of transgene technology in the fields of high level biologies, more and more attention was payed to gene silence. Gene silence can take place at the phase of transcription and post\|transcription.With the results of methylation,repeated copies and homonegeous sequence of inner genes , trans\|gene are silenced. There are many kinds of mechanisms of gene silencing and here, the mechanisms explaining the gene silence and some prevention measures were summarized in this paper.

关 键 词： 基因沉默 转录 甲基化

领　　域： [生物学]